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An Immortalized Hepatocyte-Like Cell Line (imHC) Accommodated Complete Viral Lifecycle, Viral Persistence Form, cccDNA and Eventual Spreading of a Clinically-Isolated HBV

More than 350 million people worldwide have been persistently infected with the hepatitis B virus (HBV). Chronic HBV infection could advance toward liver cirrhosis and hepatocellular carcinoma. The intervention with prophylactic vaccine and conventional treatment could suppress HBV, but could not co...

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Bibliographic Details
Published in:Viruses
Main Authors: Sa-ngiamsuntorn, Khanit, Thongsri, Piyanoot, Pewkliang, Yongyut, Wongkajornsilp, Adisak, Kongsomboonchoke, Pattida, Suthivanich, Phichaya, Borwornpinyo, Suparerk, Hongeng, Suradej
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832882/
https://ncbi.nlm.nih.gov/pubmed/31623162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11100952
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