Inhibition of fatty acid amide hydrolase by BIA 10-2474 in rat brain

In a recent clinical trial, the drug BIA 10-2474, a putative fatty acid amide hydrolase(FAAH) inhibitor, was responsible for severe adverse events (SAEs), including one death. To date, there has been little reliable information divulged about the potency of BIA 10-2474 at FAAH in the central nervous...

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Dades bibliogràfiques
Publicat a:J Cereb Blood Flow Metab
Autors principals: Tong, Junchao, Mizrahi, Romina, Houle, Sylvain, Kish, Stephen J, Boileau, Isabelle, Nobrega, Jose, Rusjan, Pablo M, Wilson, Alan A
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2016
Matèries:
Brief Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669339/
https://ncbi.nlm.nih.gov/pubmed/27650910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16668890
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