Inhibition of fatty acid amide hydrolase by BIA 10-2474 in rat brain

In a recent clinical trial, the drug BIA 10-2474, a putative fatty acid amide hydrolase(FAAH) inhibitor, was responsible for severe adverse events (SAEs), including one death. To date, there has been little reliable information divulged about the potency of BIA 10-2474 at FAAH in the central nervous...

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書目詳細資料
發表在:J Cereb Blood Flow Metab
Main Authors: Tong, Junchao, Mizrahi, Romina, Houle, Sylvain, Kish, Stephen J, Boileau, Isabelle, Nobrega, Jose, Rusjan, Pablo M, Wilson, Alan A
格式: Artigo
語言:Inglês
出版: SAGE Publications 2016
主題:
Brief Communication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669339/
https://ncbi.nlm.nih.gov/pubmed/27650910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16668890
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