Calcium channel blocker use and risk of prostate cancer by TMPRSS2:ERG gene fusion status

BACKGROUND: Calcium channel blockers (CCBs) may affect prostate cancer (PCa) growth by various mechanisms including those related to androgens. The fusion of the androgen-regulated gene TMPRSS2 and the oncogene ERG (TMPRSS2:ERG or T2E) is common in PCa, and prostate tumors that harbor the gene fusio...

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Bibliographic Details
Published in:Prostate
Main Authors: Geybels, Milan S., McCloskey, Karen D., Mills, Ian G., Stanford, Janet L.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668682/
https://ncbi.nlm.nih.gov/pubmed/27753122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23267
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