Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding

To divide, most animal cells drastically change shape and round up against extracellular confinement. Mitotic cells facilitate this process by generating intracellular pressure, which the contractile actomyosin cortex directs into shape. Here, we introduce a genome-scale microcantilever- and RNAi-ba...

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Publicat a:Nat Commun
Autors principals: Toyoda, Yusuke, Cattin, Cedric J., Stewart, Martin P., Poser, Ina, Theis, Mirko, Kurzchalia, Teymuras V., Buchholz, Frank, Hyman, Anthony A., Müller, Daniel J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668354/
https://ncbi.nlm.nih.gov/pubmed/29097687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01147-6
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