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Multi-scale computational study of the mechanical regulation of cell mitotic rounding in epithelia

Mitotic rounding during cell division is critical for preventing daughter cells from inheriting an abnormal number of chromosomes, a condition that occurs frequently in cancer cells. Cells must significantly expand their apical area and transition from a polygonal to circular apical shape to achieve...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Nematbakhsh, Ali, Sun, Wenzhao, Brodskiy, Pavel A., Amiri, Aboutaleb, Narciso, Cody, Xu, Zhiliang, Zartman, Jeremiah J., Alber, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460904/
https://ncbi.nlm.nih.gov/pubmed/28531187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005533
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