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Multi-scale computational study of the mechanical regulation of cell mitotic rounding in epithelia

Mitotic rounding during cell division is critical for preventing daughter cells from inheriting an abnormal number of chromosomes, a condition that occurs frequently in cancer cells. Cells must significantly expand their apical area and transition from a polygonal to circular apical shape to achieve...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Nematbakhsh, Ali, Sun, Wenzhao, Brodskiy, Pavel A., Amiri, Aboutaleb, Narciso, Cody, Xu, Zhiliang, Zartman, Jeremiah J., Alber, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460904/
https://ncbi.nlm.nih.gov/pubmed/28531187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005533
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