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Epithelial organ shape is generated by patterned actomyosin contractility and maintained by the extracellular matrix

Epithelial sheets define organ architecture during development. Here, we employed an iterative multiscale computational modeling and quantitative experimental approach to decouple direct and indirect effects of actomyosin-generated forces, nuclear positioning, extracellular matrix, and cell-cell adh...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS Comput Biol
Päätekijät: Nematbakhsh, Ali, Levis, Megan, Kumar, Nilay, Chen, Weitao, Zartman, Jeremiah J., Alber, Mark
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480841/
https://ncbi.nlm.nih.gov/pubmed/32817654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008105
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