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Protein Kinase C as a Tumor Suppressor
Protein kinase C (PKC) has historically been considered an oncoprotein. This stems in large part from the discovery in the early 1980s that PKC is directly activated by tumor-promoting phorbol esters. Yet three decades of clinical trials using PKC inhibitors in cancer therapies not only failed, but...
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| Publicado no: | Semin Cancer Biol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5668200/ https://ncbi.nlm.nih.gov/pubmed/28476658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2017.04.017 |
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