Functional imaging in combination with mutation status aids prediction of response to inhibiting B-cell receptor signaling in lymphoma

Aberrant B-cell receptor (BCR) signaling is known to contribute to malignant transformation. Two small molecule inhibitors targeting BCR pathway signaling include ibrutinib, a Bruton’s tyrosine kinase (BTK) inhibitor, and idelalisib, a specific Phosphatidylinositol-4,5-bisphosphate 3-kinase delta (P...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jacobs, Laura, Habringer, Stefan, Slawska, Jolanta, Huber, Katharina, Hauf, Elke, Li, Zhoulei, Refaeli, Yosef, Schwaiger, Markus, Rudelius, Martina, Walch, Axel, Keller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668008/
https://ncbi.nlm.nih.gov/pubmed/29108275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20551
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