S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting microRNA 34a/b-methionine adenosyltransferase 2A/2B axis

MicroRNA-34a (miR-34a) is down-regulated in colorectal cancers (CRC) and required for interleukin-6 (IL-6)-induced CRC metastasis. Mice lacking miR-34a developed more invasive cancer in a colitis-associated cancer model. In the same model, S-adenosylmethionine (SAMe) and methylthioadenosine (MTA) in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tomasi, Maria Lauda, Cossu, Carla, Spissu, Ylenia, Floris, Andrea, Ryoo, Minjung, Iglesias-Ara, Ainhoa, Wang, Qiang, Pandol, Stephen J., Bhowmick, Neil A., Seki, Ekihiro, Posadas, Edwin M., Lu, Shelly C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668003/
https://ncbi.nlm.nih.gov/pubmed/29108270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20234
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados