Inhibition of porcupine prolongs metastasis free survival in a mouse xenograft model of Ewing sarcoma

The most pressing unmet clinical need for patients with Ewing sarcoma (ES) is the prevention and treatment of metastasis. The Wnt signaling pathway regulates a number of cellular functions associated with metastasis, including proliferation, motility, and stem cell self-renewal. Functional interacti...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Hayashi, Masanori, Baker, Alissa, Goldstein, Seth D., Albert, Catherine M., Jackson, Kyle W., McCarty, Gregory, Kahlert, Ulf D., Loeb, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
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Priority Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667961/
https://ncbi.nlm.nih.gov/pubmed/29108227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19432
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