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WT1 regulates angiogenesis in Ewing Sarcoma

Angiogenesis is required for tumor growth. WT1, a protein that affects both mRNA transcription and splicing, has recently been shown to regulate expression of vascular endothelial growth factor (VEGF), one of the major mediators of angiogenesis. In the present study, we tested the hypothesis that WT...

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Autors principals: Katuri, Varalakshmi, Gerber, Stephanie, Qiu, Xiaofei, McCarty, Gregory, Goldstein, Seth D., Hammers, Hans, Montgomery, Elizabeth, Chen, Allen R., Loeb, David M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058017/
https://ncbi.nlm.nih.gov/pubmed/24810959
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