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Caspase-8 expression is predictive of tumour response to death receptor 5 agonist antibody in Ewing's sarcoma
BACKGROUND: Despite good initial response to chemotherapy, 30% of Ewing's sarcoma (EWS) patients with localised tumours develop recurrent disease, associated with poor prognosis. The aim of this study was to address this challenge by conducting preclinical evaluation of a death receptor targete...
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| Publié dans: | Br J Cancer |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4578089/ https://ncbi.nlm.nih.gov/pubmed/26291055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.298 |
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