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Metastatic melanoma imaging using a novel Tc-99m-labeled lactam-cyclized alpha-MSH peptide
The purpose of this study was to determine the metastatic melanoma imaging property of (99m)Tc(EDDA)-HYNIC-Aoc-Nle-CycMSH(hex) {hydrazinonicotinamide-8-aminooctanoic acid-Nle-c[Asp-His-DPhe-Arg-Trp-Lys]-CONH(2)}. HYNIC-Aoc-Nle-CycMSH(hex) was synthesized using fluorenylmethyloxy carbonyl (Fmoc) chem...
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| Publicado no: | Bioorg Med Chem Lett |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5667642/ https://ncbi.nlm.nih.gov/pubmed/29054361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.10.022 |
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