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Imaging human melanoma using a novel Tc-99m-labeled lactam bridge-cyclized alpha-MSH peptide
In this study, the human melanoma targeting property of (99m)Tc(EDDA)-HYNIC-AocNle-CycMSH(hex) {hydrazinonicotinamide-8-aminooctanoic acid-Nle-c[Asp-His-DPhe-Arg-Trp-Lys]-CONH(2)} was determined in M21 human melanoma-xenografts to demonstrate its potential for human melanoma imaging. The IC(50) valu...
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| Publicado no: | Bioorg Med Chem Lett |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5018458/ https://ncbi.nlm.nih.gov/pubmed/27568083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.08.042 |
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