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Melanoma targeting property of a Lu-177-labeled lactam bridge-cyclized alpha-MSH peptide

The purpose of this study was to determine the melanoma targeting property of (177)Lu-DOTA-GGNle-CycMSH(hex) in B16/F1 melanoma-bearing C57 mice. (177)Lu-DOTA-GGNle-CycMSH(hex) exhibited high receptor-mediated melanoma uptake and fast urinary clearance. The tumor uptake of (177)Lu-DOTA-GGNle-CycMSH(...

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Bibliografiske detaljer
Main Authors: Guo, Haixun, Miao, Yubin
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635095/
https://ncbi.nlm.nih.gov/pubmed/23473679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.02.069
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