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Melanoma targeting property of a Lu-177-labeled lactam bridge-cyclized alpha-MSH peptide
The purpose of this study was to determine the melanoma targeting property of (177)Lu-DOTA-GGNle-CycMSH(hex) in B16/F1 melanoma-bearing C57 mice. (177)Lu-DOTA-GGNle-CycMSH(hex) exhibited high receptor-mediated melanoma uptake and fast urinary clearance. The tumor uptake of (177)Lu-DOTA-GGNle-CycMSH(...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635095/ https://ncbi.nlm.nih.gov/pubmed/23473679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.02.069 |
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