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Gallium-67-Labeled Lactam Bridge-Cyclized Alpha-MSH Peptides with Enhanced Melanoma Uptake and Reduced Renal Uptake

The purpose of this study was to examine the melanoma targeting and pharmacokinetic properties of (67)Ga-DOTA-GGNle-CycMSH(hex) {(67)Ga-1,4,7,10-tetraazacyclononane-1,4,7,10-tetraacetic acid-Gly-Gly-Nle-c[Asp-His-dPhe-Arg-Trp-Lys]-CONH(2)} and (67)Ga-NOTA-GGNle-CycMSH(hex) {(67)Ga-1,4,7-triazacyclon...

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Autors principals: Guo, Haixun, Gallazzi, Fabio, Miao, Yubin
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440555/
https://ncbi.nlm.nih.gov/pubmed/22621181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300191z
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