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A high-throughput screening strategy to identify inhibitors of SSB protein-protein interactions in an academic screening facility

Antibiotic-resistant bacterial infections are increasingly prevalent worldwide and there is an urgent need for novel classes of antibiotics capable of overcoming existing resistance mechanisms. One potential antibiotic target is the bacterial single-stranded DNA binding protein (SSB) which serves as...

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Detalles Bibliográficos
Publicado en:SLAS Discov
Main Authors: Voter, Andrew F., Killoran, Michael P., Ananiev, Gene E., Wildman, Scott A., Hoffmann, F. Michael, Keck, James L.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667550/
https://ncbi.nlm.nih.gov/pubmed/28570838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555217712001
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