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The mechanistic target of rapamycin (mTOR) pathway and S6 Kinase mediate diazoxide preconditioning in primary rat cortical neurons

We examined the role of the mechanistic target of rapamycin (mTOR) pathway in delayed diazoxide (DZ)-induced preconditioning of cultured rat primary cortical neurons. Neurons were treated for three days with 500 μM DZ or feeding medium and then exposed to three hours of continuous normoxia in DMEM w...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurochem
Hauptverfasser: Dutta, Somhrita, Rutkai, Ibolya, Katakam, Prasad V. G., Busija, David W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667543/
https://ncbi.nlm.nih.gov/pubmed/26016889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13181
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