Curative Multicycle Radioimmunotherapy Monitored by Quantitative SPECT/CT-Based Theranostics, Using Bispecific Antibody Pretargeting Strategy in Colorectal Cancer

Radioimmunotherapy of solid tumors using antibody-targeted radionuclides has been limited by low therapeutic indices (TIs). We recently reported a novel 3-step pretargeted radioimmunotherapy (PRIT) strategy based on a glycoprotein A33 (GPA33)–targeting bispecific antibody and a small-molecule radioa...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Nucl Med
Autori principali: Cheal, Sarah M., Fung, Edward K., Patel, Mitesh, Xu, Hong, Guo, Hong-fen, Zanzonico, Pat B., Monette, Sebastien, Wittrup, K. Dane, Cheung, Nai-Kong V., Larson, Steven M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society of Nuclear Medicine 2017
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666642/
https://ncbi.nlm.nih.gov/pubmed/28705917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.117.193250
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi