UbcD1 regulates Hedgehog signaling by directly modulating Ci ubiquitination and processing

The Hh pathway controls many morphogenetic processes in metazoans and plays important roles in numerous pathologies and in cancer. Hh signaling is mediated by the activity of the Gli/Ci family of transcription factors. Several studies in Drosophila have shown that ubiquitination by the ubiquitin E3...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO Rep
Prif Awduron: Pan, Chenyu, Xiong, Yue, Lv, Xiangdong, Xia, Yuanxin, Zhang, Shuo, Chen, Hao, Fan, Jialin, Wu, Wenqing, Liu, Feng, Wu, Hailong, Zhou, Zhaocai, Zhang, Lei, Zhao, Yun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Scientific Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666607/
https://ncbi.nlm.nih.gov/pubmed/28887318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643289
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