Asymmetric Cryo-EM Structure of Anthrax Toxin Protective Antigen Pore with Lethal Factor N-Terminal Domain

The anthrax lethal toxin consists of protective antigen (PA) and lethal factor (LF). Understanding both the PA pore formation and LF translocation through the PA pore is crucial to mitigating and perhaps preventing anthrax disease. To better understand the interactions of the LF-PA engagement comple...

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Bibliografske podrobnosti
izdano v:Toxins (Basel)
Main Authors: Machen, Alexandra J., Akkaladevi, Narahari, Trecazzi, Caleb, O’Neil, Pierce T., Mukherjee, Srayanta, Qi, Yifei, Dillard, Rebecca, Im, Wonpil, Gogol, Edward P., White, Tommi A., Fisher, Mark T.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666345/
https://ncbi.nlm.nih.gov/pubmed/28937604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9100298
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