Asymmetric Cryo-EM Structure of Anthrax Toxin Protective Antigen Pore with Lethal Factor N-Terminal Domain

The anthrax lethal toxin consists of protective antigen (PA) and lethal factor (LF). Understanding both the PA pore formation and LF translocation through the PA pore is crucial to mitigating and perhaps preventing anthrax disease. To better understand the interactions of the LF-PA engagement comple...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Machen, Alexandra J., Akkaladevi, Narahari, Trecazzi, Caleb, O’Neil, Pierce T., Mukherjee, Srayanta, Qi, Yifei, Dillard, Rebecca, Im, Wonpil, Gogol, Edward P., White, Tommi A., Fisher, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666345/
https://ncbi.nlm.nih.gov/pubmed/28937604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9100298
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