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Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma

Hepatoblastoma is the most common malignant pediatric liver cancer. Histological evaluation of tumor biopsies is used to distinguish among the different subtypes of hepatoblastoma, with fetal and embryonal representing the two main epithelial components. With frequent CTNNB1 mutations, hepatoblastom...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO Mol Med
Prif Awduron: Crippa, Stefania, Ancey, Pierre‐Benoit, Vazquez, Jessica, Angelino, Paolo, Rougemont, Anne‐Laure, Guettier, Catherine, Zoete, Vincent, Delorenzi, Mauro, Michielin, Olivier, Meylan, Etienne
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666308/
https://ncbi.nlm.nih.gov/pubmed/28923827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707814
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