Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma

Hepatoblastoma is the most common malignant pediatric liver cancer. Histological evaluation of tumor biopsies is used to distinguish among the different subtypes of hepatoblastoma, with fetal and embryonal representing the two main epithelial components. With frequent CTNNB1 mutations, hepatoblastom...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Crippa, Stefania, Ancey, Pierre‐Benoit, Vazquez, Jessica, Angelino, Paolo, Rougemont, Anne‐Laure, Guettier, Catherine, Zoete, Vincent, Delorenzi, Mauro, Michielin, Olivier, Meylan, Etienne
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666308/
https://ncbi.nlm.nih.gov/pubmed/28923827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707814
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