Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma

Hepatoblastoma is the most common malignant pediatric liver cancer. Histological evaluation of tumor biopsies is used to distinguish among the different subtypes of hepatoblastoma, with fetal and embryonal representing the two main epithelial components. With frequent CTNNB1 mutations, hepatoblastom...

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Udgivet i:EMBO Mol Med
Main Authors: Crippa, Stefania, Ancey, Pierre‐Benoit, Vazquez, Jessica, Angelino, Paolo, Rougemont, Anne‐Laure, Guettier, Catherine, Zoete, Vincent, Delorenzi, Mauro, Michielin, Olivier, Meylan, Etienne
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666308/
https://ncbi.nlm.nih.gov/pubmed/28923827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707814
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