Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma

Hepatoblastoma is the most common malignant pediatric liver cancer. Histological evaluation of tumor biopsies is used to distinguish among the different subtypes of hepatoblastoma, with fetal and embryonal representing the two main epithelial components. With frequent CTNNB1 mutations, hepatoblastom...

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Publicat a:EMBO Mol Med
Autors principals: Crippa, Stefania, Ancey, Pierre‐Benoit, Vazquez, Jessica, Angelino, Paolo, Rougemont, Anne‐Laure, Guettier, Catherine, Zoete, Vincent, Delorenzi, Mauro, Michielin, Olivier, Meylan, Etienne
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666308/
https://ncbi.nlm.nih.gov/pubmed/28923827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707814
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