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Roles for the VCP co-factors Npl4 and Ufd1 in neuronal function in Drosophila melanogaster
The VCP-Ufd1-Npl4 complex regulates proteasomal processing within cells by delivering ubiquitinated proteins to the proteasome for degradation. Mutations in VCP are associated with two neurodegenerative diseases, amyotrophic lateral sclerosis (ALS) and inclusion body myopathy with Paget's disea...
में बचाया:
| में प्रकाशित: | J Genet Genomics |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Science press ;, Elsevier
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5666124/ https://ncbi.nlm.nih.gov/pubmed/29037990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgg.2017.06.003 |
| टैग : |
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