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Omega-3 fatty acids, lipids, and apoE lipidation in Alzheimer’s disease: a rationale for multi-nutrient dementia prevention

In the last decade, it has become obvious that Alzheimer’s disease (AD) is closely linked to changes in lipids or lipid metabolism. One of the main pathological hallmarks of AD is amyloid-β (Aβ) deposition. Aβ is derived from sequential proteolytic processing of the amyloid precursor protein (APP)....

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Vydáno v:J Lipid Res
Hlavní autoři: Grimm, Marcus O. W., Michaelson, Daniel M., Hartmann, Tobias
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665674/
https://ncbi.nlm.nih.gov/pubmed/28528321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R076331
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