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Optogenetic interrogation of integrin αVβ3 function in endothelial cells
The integrin αVβ3 is reported to promote angiogenesis in some model systems but not in others. Here, we used optogenetics to study the effects of αVβ3 interaction with the intracellular adapter kindlin-2 (Fermt2) on endothelial cell functions potentially relevant to angiogenesis. Because interaction...
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| Published in: | J Cell Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Company of Biologists Ltd
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5665447/ https://ncbi.nlm.nih.gov/pubmed/28864764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.205203 |
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