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Optogenetic interrogation of integrin αVβ3 function in endothelial cells

The integrin αVβ3 is reported to promote angiogenesis in some model systems but not in others. Here, we used optogenetics to study the effects of αVβ3 interaction with the intracellular adapter kindlin-2 (Fermt2) on endothelial cell functions potentially relevant to angiogenesis. Because interaction...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Sci
Egile Nagusiak: Liao, Zhongji, Kasirer-Friede, Ana, Shattil, Sanford J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Ltd 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665447/
https://ncbi.nlm.nih.gov/pubmed/28864764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.205203
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