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Optogenetic interrogation of integrin αVβ3 function in endothelial cells

The integrin αVβ3 is reported to promote angiogenesis in some model systems but not in others. Here, we used optogenetics to study the effects of αVβ3 interaction with the intracellular adapter kindlin-2 (Fermt2) on endothelial cell functions potentially relevant to angiogenesis. Because interaction...

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Bibliografske podrobnosti
izdano v:J Cell Sci
Main Authors: Liao, Zhongji, Kasirer-Friede, Ana, Shattil, Sanford J.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665447/
https://ncbi.nlm.nih.gov/pubmed/28864764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.205203
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