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Gambogenic Acid Exerts Antitumor Activity in Hypoxic Multiple Myeloma Cells by Regulation of miR-21

Hypoxia is an inseparable component of the bone marrow (BM) microenvironment, accounting for aggressive tumor behavior and poor prognosis of multiple myeloma (MM). Gambogenic acid (GNA) has proven to be an attractive option for treatment of tumors due to its tumor suppressive activity. Herein, we fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cancer
Hauptverfasser: Liu, Ping, Wu, Xue, Dai, Lu, Ge, Zheng, Gao, Chong, Zhang, Hongming, Wang, Fei, Zhang, Xiaoping, Chen, Baoan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665045/
https://ncbi.nlm.nih.gov/pubmed/29158801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.19290
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