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Gambogenic acid synergistically potentiates bortezomib-induced apoptosis in multiple myeloma

Background: Although the introduction of protease inhibitor bortezomib (BTZ) and immunomodulatory agent lenalidomide has led to improved outcomes in patients with multiple myeloma (MM), the disease remains incurable. Gambogenic acid (GNA), a polyprenylated xanthone isolated from the traditional Chin...

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Pubblicato in:J Cancer
Autori principali: Chen, Runzhe, Zhang, Hongming, Liu, Ping, Wu, Xue, Chen, Baoan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381173/
https://ncbi.nlm.nih.gov/pubmed/28382147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.17657
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