Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma

Proteasome inhibitor bortezomib is one of the most effective drugs currently available for the treatment of multiple myeloma (MM). However, the intrinsic and acquired resistance to bortezomib can limit its effectiveness. The activation of heat shock response has been characterized as a potential res...

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Bibliografiska uppgifter
I publikationen:Cell Stress Chaperones
Huvudupphovsmän: Huang, Lingjuan, Wang, Yanmeng, Bai, Ju, Yang, Yun, Wang, Fangxia, Feng, Yuandong, Zhang, Ru, Li, Fangmei, Zhang, Peihua, Lv, Nan, Lei, Lei, Hu, Jinsong, He, Aili
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Netherlands 2020
Ämnen:
Original Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058745/
https://ncbi.nlm.nih.gov/pubmed/32026316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-020-01078-0
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