Blockade of HSP70 by VER-155008 synergistically enhances bortezomib-induced cytotoxicity in multiple myeloma

Proteasome inhibitor bortezomib is one of the most effective drugs currently available for the treatment of multiple myeloma (MM). However, the intrinsic and acquired resistance to bortezomib can limit its effectiveness. The activation of heat shock response has been characterized as a potential res...

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Bibliografiske detaljer
Udgivet i:Cell Stress Chaperones
Main Authors: Huang, Lingjuan, Wang, Yanmeng, Bai, Ju, Yang, Yun, Wang, Fangxia, Feng, Yuandong, Zhang, Ru, Li, Fangmei, Zhang, Peihua, Lv, Nan, Lei, Lei, Hu, Jinsong, He, Aili
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2020
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058745/
https://ncbi.nlm.nih.gov/pubmed/32026316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-020-01078-0
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