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Mismatch Repair Protein hMLH1, but not hMSH2, Enhances Estrogen-Induced Apoptosis of Colon Cancer Cells

Background: Epidemiological studies suggest a protective role of estrogen against colon carcinogenesis; this effect appears to be dependent on mismatch repair (MMR) status. However, the underlying mechanism remains unclear. This study investigated the role of MMR proteins in apoptosis of colon cance...

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Dettagli Bibliografici
Pubblicato in:J Cancer
Autori principali: Jin, Peng, Wang, De-zhi, Lyu, Chen-xi, Wang, Ya-ting, He, Yu-qi, Sheng, Jian-qiu, Li, Xuhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665039/
https://ncbi.nlm.nih.gov/pubmed/29158795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.20833
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