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Human papillomavirus oncogenes reprogram the cervical cancer microenvironment independently of and synergistically with estrogen

High-risk human papillomaviruses (HPVs) infect epithelial cells and are causally associated with cervical cancer, but HPV infection is not sufficient for carcinogenesis. Previously, we reported that estrogen signaling in the stromal tumor microenvironment is associated with cervical cancer maintenan...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Spurgeon, Megan E., den Boon, Johan A., Horswill, Mark, Barthakur, Sonalee, Forouzan, Omid, Rader, Janet S., Beebe, David J., Roopra, Avtar, Ahlquist, Paul, Lambert, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664542/
https://ncbi.nlm.nih.gov/pubmed/29073104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712018114
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