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Human papillomavirus oncogenes reprogram the cervical cancer microenvironment independently of and synergistically with estrogen

High-risk human papillomaviruses (HPVs) infect epithelial cells and are causally associated with cervical cancer, but HPV infection is not sufficient for carcinogenesis. Previously, we reported that estrogen signaling in the stromal tumor microenvironment is associated with cervical cancer maintenan...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Spurgeon, Megan E., den Boon, Johan A., Horswill, Mark, Barthakur, Sonalee, Forouzan, Omid, Rader, Janet S., Beebe, David J., Roopra, Avtar, Ahlquist, Paul, Lambert, Paul F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664542/
https://ncbi.nlm.nih.gov/pubmed/29073104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712018114
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