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Selective neutralization of IL-12 p40 monomer induces death in prostate cancer cells via IL-12–IFN-γ
Cancer cells are adept at evading cell death, but the underlying mechanisms are poorly understood. IL-12 plays a critical role in the early inflammatory response to infection and in the generation of T-helper type 1 cells, favoring cell-mediated immunity. IL-12 is composed of two different subunits,...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5664500/ https://ncbi.nlm.nih.gov/pubmed/29073075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705536114 |
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