The ADAMTS13(1239–1253) peptide is a dominant HLA-DR1-restricted CD4(+) T-cell epitope

Acquired thrombotic thrombocytopenic purpura is a rare and severe disease characterized by auto-antibodies directed against “A Disintegrin And Metalloproteinase with Thrombospondin type 1 repeats, 13(th) member" (ADAMTS13), a plasma protein involved in hemostasis. Involvement of CD4(+) T cells...

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Publicado no:Haematologica
Main Authors: Gilardin, Laurent, Delignat, Sandrine, Peyron, Ivan, Ing, Mathieu, Lone, Yu-Chun, Gangadharan, Bagirath, Michard, Baptiste, Kherabi, Yousra, Sharma, Meenu, Pashov, Anastas, Latouche, Jean-Baptiste, Hamieh, Mohamad, Toutirais, Olivier, Loiseau, Pascale, Galicier, Lionel, Veyradier, Agnès, Kaveri, Srini, Maillère, Bernard, Coppo, Paul, Lacroix-Desmazes, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664387/
https://ncbi.nlm.nih.gov/pubmed/28751567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.136671
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