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CD47-CAR-T Cells Effectively Kill Target Cancer Cells and Block Pancreatic Tumor Growth

CD47 is a glycoprotein of the immunoglobulin superfamily that is often overexpressed in different types of hematological and solid cancer tumors and plays important role in blocking phagocytosis, increased tumor survival, metastasis and angiogenesis. In the present report, we designed CAR (chimeric...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Golubovskaya, Vita, Berahovich, Robert, Zhou, Hua, Xu, Shirley, Harto, Hizkia, Li, Le, Chao, Cheng-Chi, Mao, Mike Ming, Wu, Lijun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664078/
https://ncbi.nlm.nih.gov/pubmed/29065481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9100139
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