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Different Subsets of T Cells, Memory, Effector Functions, and CAR-T Immunotherapy

This review is focused on different subsets of T cells: CD4 and CD8, memory and effector functions, and their role in CAR-T therapy––a cellular adoptive immunotherapy with T cells expressing chimeric antigen receptor. The CAR-T cells recognize tumor antigens and induce cytotoxic activities against t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Golubovskaya, Vita, Wu, Lijun
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810120/
https://ncbi.nlm.nih.gov/pubmed/26999211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8030036
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