CAR-T Cells Based on Novel BCMA Monoclonal Antibody Block Multiple Myeloma Cell Growth

The cell-surface protein B cell maturation antigen (BCMA, CD269) has emerged as a promising target for CAR-T cell therapy for multiple myeloma. In order to create a novel BCMA CAR, we generated a new BCMA monoclonal antibody, clone 4C8A. This antibody exhibited strong and selective binding to human...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cancers (Basel)
Hlavní autoři: Berahovich, Robert, Zhou, Hua, Xu, Shirley, Wei, Yuehua, Guan, Jasper, Guan, Jian, Harto, Hizkia, Fu, Shuxiang, Yang, Kaihuai, Zhu, Shuying, Li, Le, Wu, Lijun, Golubovskaya, Vita
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162381/
https://ncbi.nlm.nih.gov/pubmed/30208593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10090323
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky