Candidate synthetic lethality partners to PARP inhibitors in the treatment of ovarian clear cell cancer

Inhibitors of poly(ADP-ribose) polymerase (PARP) are new types of personalized treatment of relapsed platinum-sensitive ovarian cancer harboring BRCA1/2 mutations. Ovarian clear cell cancer (CCC), a subset of ovarian cancer, often appears as low-stage disease with a higher incidence among Japanese....

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Detalhes bibliográficos
Publicado no:Biomed Rep
Main Authors: Kawahara, Naoki, Ogawa, Kenji, Nagayasu, Mika, Kimura, Mai, Sasaki, Yoshikazu, Kobayashi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663977/
https://ncbi.nlm.nih.gov/pubmed/29109859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2017.990
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