Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

Overconsumption of high-fat diet (HFD) and sugar-sweetened beverages are risk factors for developing obesity, insulin resistance, and fatty liver disease. Here we have dissected mechanisms underlying this association using mice fed either chow or HFD with or without fructose- or glucose-supplemented...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Softic, Samir, Gupta, Manoj K., Wang, Guo-Xiao, Fujisaka, Shiho, O’Neill, Brian T., Rao, Tata Nageswara, Willoughby, Jennifer, Harbison, Carole, Fitzgerald, Kevin, Ilkayeva, Olga, Newgard, Christopher B., Cohen, David E., Kahn, C. Ronald
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663363/
https://ncbi.nlm.nih.gov/pubmed/28972537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94585
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