Thy-1 interaction with Fas in lipid rafts regulates fibroblast apoptosis and lung injury resolution

Thy-1-negative lung fibroblasts are resistant to apoptosis. The mechanisms governing this process and its relevance to fibrotic remodeling remain poorly understood. By using either sorted or transfected lung fibroblasts, we found that Thy-1 expression is associated with downregulation of anti-apopto...

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Bibliografske podrobnosti
izdano v:Lab Invest
Main Authors: Liu, Xiaoqiu, Wong, Simon S., Taype, Carmen A., Kim, Jeeyeon, Shentu, Tzu-Pin, Espinoza, Celia R., Finley, Cameron, Bradley, John E., Head, Brian P., Patel, Hemal H., Mah, Emma J., Hagood, James S.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663248/
https://ncbi.nlm.nih.gov/pubmed/28165468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2016.145
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