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Thy-1 interaction with Fas in lipid rafts regulates fibroblast apoptosis and lung injury resolution

Thy-1-negative lung fibroblasts are resistant to apoptosis. The mechanisms governing this process and its relevance to fibrotic remodeling remain poorly understood. By using either sorted or transfected lung fibroblasts, we found that Thy-1 expression is associated with downregulation of anti-apopto...

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Publicat a:Lab Invest
Autors principals: Liu, Xiaoqiu, Wong, Simon S., Taype, Carmen A., Kim, Jeeyeon, Shentu, Tzu-Pin, Espinoza, Celia R., Finley, Cameron, Bradley, John E., Head, Brian P., Patel, Hemal H., Mah, Emma J., Hagood, James S.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663248/
https://ncbi.nlm.nih.gov/pubmed/28165468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2016.145
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