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Yeast Srs2 helicase promotes redistribution of single-stranded DNA-bound RPA and Rad52 in homologous recombination regulation

Srs2 is a Super-Family 1 helicase that promotes genome stability by dismantling toxic DNA recombination intermediates. However, the mechanisms by which Srs2 remodels or resolves recombination intermediates remain poorly understood. Here, single molecule imaging is used to visualize Srs2 in real time...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: De Tullio, Luisina, Kaniecki, Kyle, Kwon, YoungHo, Crickard, J. Brooks, Sung, Patrick, Greene, Eric C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663194/
https://ncbi.nlm.nih.gov/pubmed/29045827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.073
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