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Yeast Srs2 helicase promotes redistribution of single-stranded DNA-bound RPA and Rad52 in homologous recombination regulation

Srs2 is a Super-Family 1 helicase that promotes genome stability by dismantling toxic DNA recombination intermediates. However, the mechanisms by which Srs2 remodels or resolves recombination intermediates remain poorly understood. Here, single molecule imaging is used to visualize Srs2 in real time...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: De Tullio, Luisina, Kaniecki, Kyle, Kwon, YoungHo, Crickard, J. Brooks, Sung, Patrick, Greene, Eric C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663194/
https://ncbi.nlm.nih.gov/pubmed/29045827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.073
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