Yeast Srs2 helicase promotes redistribution of single-stranded DNA-bound RPA and Rad52 in homologous recombination regulation

Srs2 is a Super-Family 1 helicase that promotes genome stability by dismantling toxic DNA recombination intermediates. However, the mechanisms by which Srs2 remodels or resolves recombination intermediates remain poorly understood. Here, single molecule imaging is used to visualize Srs2 in real time...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: De Tullio, Luisina, Kaniecki, Kyle, Kwon, YoungHo, Crickard, J. Brooks, Sung, Patrick, Greene, Eric C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663194/
https://ncbi.nlm.nih.gov/pubmed/29045827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.073
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