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Dissociation of Rad51 presynaptic complexes and heteroduplex DNA joints by tandem assemblies of Srs2
Srs2 is a superfamily 1 (SF1) helicase and antirecombinase that is required for genome integrity. However, the mechanisms that regulate Srs2 remain poorly understood. Here, we visualize Srs2 as it acts upon single-stranded DNA (ssDNA) bound by the Rad51 recombinase. We demonstrate that Srs2 is a pro...
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| Izdano u: | Cell Rep |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5734666/ https://ncbi.nlm.nih.gov/pubmed/29241544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.047 |
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