Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas

Pediatric high-grade gliomas (pHGGs) are aggressive neoplasms representing approximately 20% of brain tumors in children. Current therapies offer limited disease control, and patients have a poor prognosis. Empiric use of targeted therapy, especially at progression, is increasingly practiced despite...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Salloum, Ralph, McConechy, Melissa K., Mikael, Leonie G., Fuller, Christine, Drissi, Rachid, DeWire, Mariko, Nikbakht, Hamid, De Jay, Nicolas, Yang, Xiaodan, Boue, Daniel, Chow, Lionel M. L., Finlay, Jonathan L., Gayden, Tenzin, Karamchandani, Jason, Hummel, Trent R., Olshefski, Randal, Osorio, Diana S., Stevenson, Charles, Kleinman, Claudia L., Majewski, Jacek, Fouladi, Maryam, Jabado, Nada
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663045/
https://ncbi.nlm.nih.gov/pubmed/29084603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0479-8
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