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Monitoring the Retention of Human PCNA at Primer/Template junctions by Proteins that Bind Single-stranded DNA

In humans, PCNA sliding clamps encircling DNA coordinate various aspects of DNA metabolism throughout the cell cycle. A critical aspect of this is restricting PCNA to the vicinity of its DNA target site. For example, PCNA must be maintained at/near primer/template (P/T) junctions during DNA synthesi...

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Publicat a:Biochemistry
Autors principals: Hedglin, Mark, Aitha, Mahesh, Benkovic, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662943/
https://ncbi.nlm.nih.gov/pubmed/28590137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00386
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